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minoHealth.ai: A Clinical Evaluation Of Deep Learning Systems For the Diagnosis of Pleural Effusion and Cardiomegaly In Ghana, Vietnam and the United States of America

2022-10-31 20:12:41
Darlington Akogo, Issah Abubakari Samori, Bashiru Babatunde Jimah, Dorothea Akosua Anim, Yaw Boateng Mensah, Benjamin Dabo Sarkodie

Abstract

A rapid and accurate diagnosis of cardiomegaly and pleural effusion is of the utmost importance to reduce mortality and medical costs. Artificial Intelligence has shown promise in diagnosing medical conditions. With this study, we seek to evaluate how well Artificial Intelligence (AI) systems, developed my minoHealth AI Labs, will perform at diagnosing cardiomegaly and pleural effusion, using chest x-rays from Ghana, Vietnam and the USA, and how well AI systems will perform when compared with radiologists working in Ghana. The evaluation dataset used in this study contained 100 images randomly selected from three datasets. The Deep Learning models were further tested on a larger Ghanaian dataset containing five hundred and sixty one (561) samples. Two AI systems were then evaluated on the evaluation dataset, whilst we also gave the same chest x-ray images within the evaluation dataset to 4 radiologists, with 5 - 20 years experience, to diagnose independently. For cardiomegaly, this http URL systems scored Area under the Receiver operating characteristic Curve (AUC-ROC) of 0.9 and 0.97 while the AUC-ROC of individual radiologists ranged from 0.77 to 0.87. For pleural effusion, the this http URL systems scored 0.97 and 0.91 whereas individual radiologists scored between 0.75 and 0.86. On both conditions, the best performing AI model outperforms the best performing radiologist by about 10%. We also evaluate the specificity, sensitivity, negative predictive value (NPV), and positive predictive value (PPV) between the this http URL systems and radiologists.

Abstract (translated)

URL

https://arxiv.org/abs/2211.00644

PDF

https://arxiv.org/pdf/2211.00644.pdf


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