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4D Deep Learning for Multiple Sclerosis Lesion Activity Segmentation

2020-04-20 11:41:01
Nils Gessert, Marcel Bengs, Julia Krüger, Roland Opfer, Ann-Christin Ostwaldt, Praveena Manogaran, Sven Schippling, Alexander Schlaefer

Abstract

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common, deep learning approaches for lesion activity have only been proposed recently. Here, a two-path architecture processes two 3D MRI volumes from two time points. In this work, we investigate whether extending this problem to full 4D deep learning using a history of MRI volumes and thus an extended baseline can improve performance. For this purpose, we design a recurrent multi-encoder-decoder architecture for processing 4D data. We find that adding more temporal information is beneficial and our proposed architecture outperforms previous approaches with a lesion-wise true positive rate of 0.84 at a lesion-wise false positive rate of 0.19.

Abstract (translated)

URL

https://arxiv.org/abs/2004.09216

PDF

https://arxiv.org/pdf/2004.09216.pdf


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