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Magnification Prior: A Self-Supervised Method for Learning Representations on Breast Cancer Histopathological Images

2022-03-15 07:54:20
Prakash Chandra Chhipa, Richa Upadhyay, Gustav Grund Pihlgren, Rajkumar Saini, Seiichi Uchida, Marcus Liwicki

Abstract

This work presents a novel self-supervised pre-training method to learn efficient representations without labels on histopathology medical images utilizing magnification factors. Other state-of-theart works mainly focus on fully supervised learning approaches that rely heavily on human annotations. However, the scarcity of labeled and unlabeled data is a long-standing challenge in histopathology. Currently, representation learning without labels remains unexplored for the histopathology domain. The proposed method, Magnification Prior Contrastive Similarity (MPCS), enables self-supervised learning of representations without labels on small-scale breast cancer dataset BreakHis by exploiting magnification factor, inductive transfer, and reducing human prior. The proposed method matches fully supervised learning state-of-the-art performance in malignancy classification when only 20% of labels are used in fine-tuning and outperform previous works in fully supervised learning settings. It formulates a hypothesis and provides empirical evidence to support that reducing human-prior leads to efficient representation learning in self-supervision. The implementation of this work is available online on GitHub - this https URL

Abstract (translated)

URL

https://arxiv.org/abs/2203.07707

PDF

https://arxiv.org/pdf/2203.07707.pdf


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