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PathologyBERT -- Pre-trained Vs. A New Transformer Language Model for Pathology Domain

2022-05-13 20:42:07
Thiago Santos, Amara Tariq, Susmita Das, Kavyasree Vayalpati, Geoffrey H. Smith, Hari Trivedi, Imon Banerjee

Abstract

Pathology text mining is a challenging task given the reporting variability and constant new findings in cancer sub-type definitions. However, successful text mining of a large pathology database can play a critical role to advance 'big data' cancer research like similarity-based treatment selection, case identification, prognostication, surveillance, clinical trial screening, risk stratification, and many others. While there is a growing interest in developing language models for more specific clinical domains, no pathology-specific language space exist to support the rapid data-mining development in pathology space. In literature, a few approaches fine-tuned general transformer models on specialized corpora while maintaining the original tokenizer, but in fields requiring specialized terminology, these models often fail to perform adequately. We propose PathologyBERT - a pre-trained masked language model which was trained on 347,173 histopathology specimen reports and publicly released in the Huggingface repository. Our comprehensive experiments demonstrate that pre-training of transformer model on pathology corpora yields performance improvements on Natural Language Understanding (NLU) and Breast Cancer Diagnose Classification when compared to nonspecific language models.

Abstract (translated)

URL

https://arxiv.org/abs/2205.06885

PDF

https://arxiv.org/pdf/2205.06885.pdf


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