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Physics-informed deep diffusion MRI reconstruction: break the bottleneck of training data in artificial intelligence

2022-10-20 16:27:54
Chen Qian, Zi Wang, Xinlin Zhang, Qingrui Cai, Taishan Kang, Boyu Jiang, Ran Tao, Zhigang Wu, Di Guo, Xiaobo Qu

Abstract

In this work, we propose a Physics-Informed Deep Diffusion magnetic resonance imaging (DWI) reconstruction method (PIDD). PIDD contains two main components: The multi-shot DWI data synthesis and a deep learning reconstruction network. For data synthesis, we first mathematically analyze the motion during the multi-shot data acquisition and approach it by a simplified physical motion model. The motion model inspires a polynomial model for motion-induced phase synthesis. Then, lots of synthetic phases are combined with a few real data to generate a large amount of training data. For reconstruction network, we exploit the smoothness property of each shot image phase as learnable convolution kernels in the k-space and complementary sparsity in the image domain. Results on both synthetic and in vivo brain data show that, the proposed PIDD trained on synthetic data enables sub-second ultra-fast, high-quality, and robust reconstruction with different b-values and undersampling patterns.

Abstract (translated)

URL

https://arxiv.org/abs/2210.11388

PDF

https://arxiv.org/pdf/2210.11388.pdf


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