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Geodesic B-Score for Improved Assessment of Knee Osteoarthritis

2021-03-12 12:16:21
Felix Ambellan, Stefan Zachow, Christoph von Tycowicz

Abstract

Three-dimensional medical imaging enables detailed understanding of osteoarthritis structural status. However, there remains a vast need for automatic, thus, reader-independent measures that provide reliable assessment of subject-specific clinical outcomes. To this end, we derive a consistent generalization of the recently proposed B-score to Riemannian shape spaces. We further present an algorithmic treatment yielding simple, yet efficient computations allowing for analysis of large shape populations with several thousand samples. Our intrinsic formulation exhibits improved discrimination ability over its Euclidean counterpart, which we demonstrate for predictive validity on assessing risks of total knee replacement. This result highlights the potential of the geodesic B-score to enable improved personalized assessment and stratification for interventions.

Abstract (translated)

URL

https://arxiv.org/abs/2104.01107

PDF

https://arxiv.org/pdf/2104.01107.pdf


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