Paper Reading AI Learner

Automated Multi-Process CTC Detection using Deep Learning

2021-09-26 21:56:34
Elena Ivanova, Kam W. Leong, Andrew F. Laine
arXiv_CV
         
Abstract

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments in object detection via Deep Learning using Mask-RCNNs and wider availability of pre-trained models have enabled sensitive tasks with limited data of such to be tackled with unprecedented accuracy. In this report, we present a novel 3-stage detection model for automated identification of Circulating Tumor Cells in multi-channel darkfield microscopic images comprised of: RetinaNet based identification of Cytokeratin (CK) stains, Mask-RCNN based cell detection of DAPI cell nuclei and Otsu thresholding to detect CD-45s. The training dataset is composed of 46 high variance data points, with 10 Negative and 36 Positive data points. The test set is composed of 420 negative data points. The final accuracy of the pipeline is 98.81%.

Abstract (translated)

URL

https://arxiv.org/abs/2109.12709

PDF

https://arxiv.org/pdf/2109.12709.pdf

Tags
3D Action Action_Localization Action_Recognition Activity Adversarial Agent Attention Autonomous Bert Boundary_Detection Caption Chat Classification CNN Compressive_Sensing Contour Contrastive_Learning Deep_Learning Denoising Detection Dialog Diffusion Drone Dynamic_Memory_Network Edge_Detection Embedding Embodied Emotion Enhancement Face Face_Detection Face_Recognition Facial_Landmark Few-Shot Gait_Recognition GAN Gaze_Estimation Gesture Gradient_Descent Handwriting Human_Parsing Image_Caption Image_Classification Image_Compression Image_Enhancement Image_Generation Image_Matting Image_Retrieval Inference Inpainting Intelligent_Chip Knowledge Knowledge_Graph Language_Model Matching Medical Memory_Networks Multi_Modal Multi_Task NAS NMT Object_Detection Object_Tracking OCR Ontology Optical_Character Optical_Flow Optimization Person_Re-identification Point_Cloud Portrait_Generation Pose Pose_Estimation Prediction QA Quantitative Quantitative_Finance Quantization Re-identification Recognition Recommendation Reconstruction Regularization Reinforcement_Learning Relation Relation_Extraction Represenation Represenation_Learning Restoration Review RNN Salient Scene_Classification Scene_Generation Scene_Parsing Scene_Text Segmentation Self-Supervised Semantic_Instance_Segmentation Semantic_Segmentation Semi_Global Semi_Supervised Sence_graph Sentiment Sentiment_Classification Sketch SLAM Sparse Speech Speech_Recognition Style_Transfer Summarization Super_Resolution Surveillance Survey Text_Classification Text_Generation Tracking Transfer_Learning Transformer Unsupervised Video_Caption Video_Classification Video_Indexing Video_Prediction Video_Retrieval Visual_Relation VQA Weakly_Supervised Zero-Shot