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Dual-Distribution Discrepancy for Anomaly Detection in Chest X-Rays

2022-06-08 14:52:27
Yu Cai (1 and 2), Hao Chen (3), Xin Yang (2), Yu Zhou (2), Kwang-Ting Cheng (1 and 3) ((1) Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong, China, (2) School of Electronic Information and Communications, Huazhong University of Science and Technology, Wuhan, China, (3) Department of Computer Science and Engineering, The Hong Kong University of Science and Technology, Hong Kong, China)

Abstract

Chest X-ray (CXR) is the most typical radiological exam for diagnosis of various diseases. Due to the expensive and time-consuming annotations, detecting anomalies in CXRs in an unsupervised fashion is very promising. However, almost all of the existing methods consider anomaly detection as a One-Class Classification (OCC) problem. They model the distribution of only known normal images during training and identify the samples not conforming to normal profile as anomalies in the testing phase. A large number of unlabeled images containing anomalies are thus ignored in the training phase, although they are easy to obtain in clinical practice. In this paper, we propose a novel strategy, Dual-distribution Discrepancy for Anomaly Detection (DDAD), utilizing both known normal images and unlabeled images. The proposed method consists of two modules, denoted as A and B. During training, module A takes both known normal and unlabeled images as inputs, capturing anomalous features from unlabeled images in some way, while module B models the distribution of only known normal images. Subsequently, the inter-discrepancy between modules A and B, and intra-discrepancy inside module B are designed as anomaly scores to indicate anomalies. Experiments on three CXR datasets demonstrate that the proposed DDAD achieves consistent, significant gains and outperforms state-of-the-art methods. Code is available at this https URL.

Abstract (translated)

URL

https://arxiv.org/abs/2206.03935

PDF

https://arxiv.org/pdf/2206.03935.pdf


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