Inpainting
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From Pixels to Policy: A Multi-Agent System for Intervention and Geo-Spatial Decision Support
2026-10-01 15:29:11Hosam Elgendy, Utkarsh MallAbstract
Urban environments are shaped by design choices with long-term implications for health, safety, and quality of life, yet evaluating proposed interventions remains costly, time-consuming, and often impractical. Existing geospatial vision methods largely focus on monitoring urban indicators from aerial and street-view imagery, rather than proposing interventions and estimating their effects on such indicators. Moving beyond recognition, we introduce the problem of discovering interventions that improve target indicators for a given aerial or street-view image. We argue that a black-box indicator model, combined with a generative editing model, can serve as an implicit digital twin for testing intervention hypotheses. We present VIDA-Geo , a multi-agent system that explores this intervention space by coordinating segmentation, diffusion-based inpainting, and indicator scoring models to produce interventions that are both perceptually realistic and aligned with real-world policies. We evaluate our system on 8 indicators across aerial and street-view imagery, measuring changes in factors such as perceived safety and greenery. Our approach outperforms existing baselines in many cases, achieving up to 2X higher perceptual quality and policy alignment scores. Finally, our model provides users with multiple candidate interventions, supporting an expert city-planner-in-the-loop workflow.
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URL
https://arxiv.org/abs/2610.01870
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Game Sound-Effect Completion with Event-Level Transformation Hints
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Creating sound effects for a new game-character skin requires a distinct acoustic identity while preserving gameplay-event roles. The challenge is to complete a coherent set of related sounds whose required degrees of redesign differ. We formulate this task as completion conditioned on base-skin audio, completed target assets, and a textual design description. We develop a pipeline to collect, process, and align corresponding events across League of Legends skins. Building on Stable Audio 3's pretrained audio prior, we fine-tune a latent inpainting model to jointly complete missing events. A signed soft retention mask encodes available audio and an adjustable transformation hint for each missing event, specifying the requested balance between retention and redesign. Experiments on held-out skins show improved reconstruction over the evaluated general-purpose audio editors. Target-derived hints further improve paired similarity, with three-level hints retaining most of the benefit of continuous guidance.
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https://arxiv.org/abs/2609.39044
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Diffusion Editing with Soft Mask: Pixel Level Redo of Image and Video with Adjustable Strength
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Diffusion models with prompt and reference image-guided editing have seen rapid progress, yet they remain too coarse for pixel-level control. One promising direction is to incorporate a soft mask that specifies spatially varying edit strengths but training such fine-grained control demands expensive pixel-wise annotations, while existing zero-shot methods often yield unsatisfactory results. We introduce SoftPaint, a new zero-shot sampling method that leverages soft masks to enable a continuous spectrum of edits, from fully preserving the original content to completely re-synthesizing the masked region. Going beyond zero-shot inpainting methods, we design a Langevin-iteration-based sampler that respects per-pixel soft mask strengths, which applies universally to image and video diffusion models, enabling tasks such as video editing. The method is gradient-free, memory-efficient, and achieves smooth, pixel-level edits across multiple image and video backbones.
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https://arxiv.org/abs/2610.00359
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Learning Semantic Inpainting for Animatable Gaussian Head Avatars
2026-09-29 18:07:26Pilseo Park, Fizza Rubab, Yiying TongAbstract
We present SInGA, a novel method for learning Semantic Inpainting for animatable Gaussian head Avatars from a single image. Existing avatar approaches often rely on multi-view observations and lack effective handling of unobserved regions in single-view settings, limiting their applicability in such scenarios. To address this, we propose a semantic inpainting framework defined in UV space for completing unobserved facial regions. Our key insight lies in the structured topology of the UV representation, which provides consistent spatial correspondences and enables reliable completion of identity-specific features using the inherent symmetry cues of human faces. We extract features from observed regions and use them to complete unobserved regions. The completed representation is then used to regress Gaussian attributes, effectively performing Gaussian inpainting. In addition, instead of relying on a single Gaussian at each surface or pixel location, we stack multiple Gaussians to enhance detail. The resulting avatar generalizes across identities without requiring per-identity optimization and can be animated with driving inputs. Experimental results show that our method generates high-quality head avatars with improved completeness and identity preservation, while supporting realistic animation and consistent rendering from unobserved views.
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URL
https://arxiv.org/abs/2609.38343
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Beyond Lip Sync: Reference-Grounded Oral Refinement for Audio-Driven Portrait Animation
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We present RGOR (Reference-Grounded Oral Refinement), an audio-driven lip-sync framework that renders the mouth of the specific person being dubbed rather than a generic one. Existing lip-sync systems follow the audio closely and keep the face recognizable, yet the mouth they render is an average mouth: the shape and texture of the lips, the arrangement of the teeth, and how much of them shows as the mouth opens are not that person's. The problem persists because nothing in current training or evaluation asks for the person's own mouth: perceptual losses accept any plausible mouth, face identity is carried mostly by the skin around it, and the released inference code of inpainting systems uses the unmasked target frame as the reference, which hides the gap. To address this, RGOR conditions every generated frame on frames from separate enrollment recordings of the same person and on HD patches of the mouth that bypass the VAE, and trains the generator against a paired judge that compares each rendered mouth with the person's reference and learns to reject a realistic mouth of someone else. We further build an evaluation protocol and use it to compare open-source and commercial lip-sync systems on held-out identities. Experiments show that RGOR achieves the best or second-best result on most metrics, and preserves the person's own lip and dental detail while keeping synchronization and the rest of the face intact.
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URL
https://arxiv.org/abs/2609.38019
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WINGS: Reference-Free Gaussian Splatting Inpainting with 3D-Native Generative Priors
2026-09-29 15:27:34No\'e Lallouet, Michael Fischer, Elie MichelAbstract
Inpainting 3D Gaussian Splatting scenes, a key challenge in 3D editing, requires generating plausible content within a masked region of 3D space. Prior approaches rely on 2D diffusion models to produce one or several inpainted reference views, making them susceptible to challenges associated with multi-view inconsistency and lengthy optimization times. Departing from these approaches, we introduce a reference-free Gaussian splatting inpainting method operating natively in 3D. Our method leverages the embedding space of a large, pre-trained 3D prior, combined with a structure completion network to feed a generative prior which reconstructs the missing region's geometry and appearance. Performing content generation entirely in 3D, it avoids the need to reconcile inconsistencies of multiple inpainted reference images, and is faster than related 2D-based methods. We demonstrate the effectiveness of our method qualitatively and quantitatively, through extensive experiments and a user study. To the best of our knowledge, this work is the first Gaussian splatting inpainting method to operate in the learned representation space of a 3D-native generative prior without relying on inpainted reference views.
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URL
https://arxiv.org/abs/2609.37816
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Targeted Visual Counterfactual Explanations for Contrastive Vision-Language Model
2026-09-29 14:08:05Van Bach Nguyen, J\"org Schl\"otterer, Christin SeiferAbstract
Current explanation methods for contrastive vision--language models such as CLIP mainly identify important regions without showing how to change the input in order to get a target prediction. We introduce \textbf{M}ask-guided \textbf{A}daptive \textbf{C}ounterfactual \textbf{E}xplanations (\mace), a targeted visual counterfactual method designed specifically for CLIP zero-shot classification. \mace constructs an editable region from either source attribution or source--target attribution differences and expands the mask only when needed to reach a specified target class. A latent diffusion inpainting model then modifies the selected region, while a frozen CLIP model provides modification guidance and anchors the remaining image content to the original input. We evaluate \mace on ImageNet, Food-101, Oxford Pets, and CUB-200. The source-mask variant achieves the highest target top-1 success rate across all four datasets, while the difference-mask variant produces the smallest pixel-level and perceptual changes and the best realism scores. Both variants improve proximity and realism over a Stable Diffusion-only baseline using the same generative backbone. These results show that adaptive mask-guided editing produces effective CLIP counterfactuals. They further reveal a tradeoff between counterfactual validity and source-image preservation.
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URL
https://arxiv.org/abs/2609.37638
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PCaPaint: Prostate Cancer Inpainting by Mitigating Shortcut Learning
2026-09-29 12:16:36Levente Lippenszky, Hongxu Yang, Marcell D\"om\"ot\"or, Krisztian Koos, L\'aszl\'o Rusk\'oAbstract
The development of AI systems for tumor-specific applications is limited by the scarcity of labeled data. Synthetic tumor inpainting offers a promising approach but faces challenges for prostate cancer MRI which contains high-resolution multi-sequence data. Although methods leveraging latent diffusion models (LDMs) enable large-volume synthesis, they are prone to shortcut learning, simply reproducing the condition image created by masking the lesion region. In this work, we introduce PCaPaint, a prostate cancer inpainting method based on LDMs that explicitly addresses this failure mode. To overcome shortcut learning that compromises synthetic tumor texture, we propose a simple yet efficient conditioning strategy in which the condition image is filled with Gaussian noise, and we provide theoretical justification. In addition, we propose a novel training objective for LDM that emphasizes the error within the lesion region. Furthermore, we introduce a multi-sequence latent design, in which T2w scans and DWI&ADC scans are compressed using two separate autoencoders to preserve their distinct frequency characteristics. Extensive experiments demonstrate that the generated synthetic data improves downstream performance in prostate lesion segmentation, patient-level classification and lesion-level detection. Furthermore, our method significantly outperforms a recent state-of-the-art LDM-based tumor inpainting method both in downstream performance and in synthetic image quality.
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URL
https://arxiv.org/abs/2609.37350
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HorizonFlow: Variable-Length Planning for Offline Goal-Conditioned RL
2026-09-29 07:23:00JunHyeok Oh, Zian Jang, Byung-Jun LeeAbstract
Recent advances in generative planning have made trajectory inpainting a promising approach to offline goal-conditioned reinforcement learning. However, these methods typically specify the planning horizon before generating plan content, even though the appropriate horizon depends on the route itself. A horizon that is too short can force infeasible transitions, whereas one that is too long can introduce redundant motion. We introduce HorizonFlow, a hierarchical planner that treats plan length as an output of generation rather than a prescribed input. Its subgoal route planner guides its action-prefix controller through a sequence of latent subgoals. Both components combine insertion-based generation with flow matching to jointly generate continuous plan content and length, using the partially generated plan to guide token insertion. HorizonFlow reuses the resulting length information to select candidates and steer generation toward shorter plans without a separate learned value model. Across Maze2D, Multi2D, and OGBench navigation and visual manipulation benchmarks, HorizonFlow achieves the highest average performance among the compared methods.
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URL
https://arxiv.org/abs/2609.36896
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Drag as Evidence: Motion-Grounded Latent Recomposition for Drag-Based Editing
2026-09-29 05:25:38Xinyu Pu, Hongsong Wang, Jie Gui, Pan ZhouAbstract
Modern image editors excel at semantic manipulation and visual synthesis, yet remain limited in precise spatial control, motivating the development of drag-based editing. However, existing drag-based methods often struggle to balance drag accuracy with natural, plausible, and intent-aligned generation. We propose MoRe-Drag, a motion-grounded drag-based editing method. Our key insight is to treat pixel-space warping as coarse motion evidence, and to inject this evidence into the generative sampling trajectory. Specifically, MoRe-Drag performs region-aware latent recomposition over refinement, inpainting, and anchor regions, coupled with stage-adaptive conditioning that progressively shifts from motion-grounded structure formation to semantic refinement. We further support an instruction-free interface by adapting the MLLM-based text encoder for drag-aware instruction inference. Experiments on DragBench-SR and DragBench-DR show that MoRe-Drag substantially improves drag precision over strong base editors and achieves superior drag accuracy among SOTA drag-based methods, while delivering strong semantic consistency and visually realistic results. Code and dataset will be publicly released.
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URL
https://arxiv.org/abs/2609.36755
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Region-Level Black-Box Defense Against Stealthy Embedding-Space Backdoors in CLIP
2026-09-25 17:26:02Ahmed Abdelnaby, Mohamed ElmahallawyAbstract
Contrastive Language--Image Pretraining (CLIP) has emerged as a dominant vision backbone due to its strong transferability and zero-shot capabilities. However, recent studies reveal a critical vulnerability: embedding-space backdoor attacks. By poisoning only a tiny fraction of image--text pairs, adversaries can implant stealthy triggers that induce targeted shifts in CLIP's joint embedding space. Unlike conventional backdoors that manipulate classifier logits, these attacks corrupt representations directly, making them highly effective under extremely low poisoning ratios and difficult to detect. Existing defenses require access to model parameters, gradients, logits, or clean validation data---assumptions that rarely hold in realistic black-box deployments. Moreover, current black-box methods struggle to accurately localize small or out-of-distribution triggers. We propose CLIPGuard, a lightweight and fully black-box defense specifically designed to mitigate embedding-space backdoors in CLIP encoders. CLIPGuard identifies malicious regions by measuring segment-wise embedding perturbations and selectively purifies only suspicious segments via semantic inpainting, preserving benign visual content and alignment quality. Extensive experiments on STL-10, ImageNet, and diverse trigger families---including BadCLIP, BadNets, blended, patch-based, and typographic attacks---demonstrate that CLIPGuard reduces attack success rates to as low as 1.05% while maintaining clean accuracy up to 86.34%, consistently outperforming existing black-box defenses, including CleanCLIP and CleanerCLIP. Our code is available this https URL
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URL
https://arxiv.org/abs/2609.31558
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Combining General and Domain-Specific Pretext Tasks for Brain MR Image Segmentation
2026-09-25 02:36:20Tasneem Nasser, Susanne Schmid, Roberto Souza, Naser El-SheimyAbstract
A key challenge in medical image analysis is the scarcity of large annotated datasets for specific populations and diseases. As deep learning models rely heavily on labeled data, effective transfer learning strategies are needed to reduce the dependence on manual annotations. Self-supervised learning has emerged as a promising approach for developing foundation models by enabling the learning of transferable feature representations from large-scale unlabeled medical imaging datasets. In this study, we investigate voxel-level brain age prediction as a domain-specific self-supervised pretext task and compare it with image inpainting, a widely used non-domain-specific alternative. We further propose a multitask self-supervised pretraining framework that jointly optimizes both objectives to learn complementary neuroimaging representations. The pretrained models are evaluated on three downstream magnetic resonance image segmentation tasks: multiple sclerosis lesion segmentation, ischemic stroke lesion segmentation, and cortical brain structure segmentation. Overall, the proposed multitask pretraining framework consistently outperformed the single-task pretrained models and training from scratch across most experimental settings, demonstrating the benefit of combining domain-specific and general self-supervised learning pretext tasks for the development of generalizable neuroimaging foundation models.\ Code Availability: The source code used in this study is publicly available at this https URL
Abstract (translated)
URL
https://arxiv.org/abs/2609.30708
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Zero-Shot Object Removal via Attention Masking, Latent Anchoring, and Refinement
2026-09-23 16:19:31Arman Taghizadeh (Institute of Cognitive Science, Osnabr\"uck University, Osnabr\"uck, Germany), Ulf Krumnack (Institute of Cognitive Science, Osnabr\"uck University, Osnabr\"uck, Germany), Kai-Uwe K\"uhnberger (Institute of Cognitive Science, Osnabr\"uck University, Osnabr\"uck, Germany)Abstract
Removing an object from a real image requires more than synthesizing plausible content within a mask: the method must suppress residual object features, preserve the unedited scene, and generate replacement content that is consistent with the surrounding background. This paper approaches object removal from a stage-based perspective and proposes a zero-shot framework for constrained latent inpainting with a frozen pretrained Stable Diffusion model, requiring no task-specific training or model fine-tuning. The method integrates SAM-based mask construction, BLIP image-caption conditioning, DDIM inversion, background-weighted masked null-text optimization, decoder self-attention masking, hard outside-mask latent anchoring, and localized renoise--denoise refinement into a unified pipeline. The method is evaluated through qualitative examples, quantitative local-consistency metrics, and ablation studies. The results demonstrate effective object removal and context-consistent replacement content. The ablations indicate that background-weighted masked NTI is particularly beneficial for structurally complex backgrounds, whereas the no-NTI variant is sufficient in other evaluated examples. Repeated refinement further reduces object remnants and boundary artifacts remaining after the primary editing pass.
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https://arxiv.org/abs/2609.28342
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TV-AudioRemover: Joint Text-Visual Guided Sound Removal with Multi-Task Hard-Mixture Curriculum
2026-09-22 08:29:41Xinyue Guo, Jianxuan Yang, Daiguo Zhou, Jiagao Hu, Yuxuan Chen, Fei Wang, Jian LuanAbstract
Visual object removal can eliminate a target from video frames, yet its acoustic trace persists in the soundtrack, causing obvious audio-visual inconsistency. Existing video inpainting models operate solely on pixels, while audio editing models, especially for the sound removal task, are typically driven by text and therefore rely on limited single-modal control, which is less effective than multimodal guidance that provides stronger semantic grounding and temporal synchronization cues. In this paper, we present Text-Visual Guided Sound Removal (TV-AudioRemover), a target sound removal framework that leverages the visually edited video together with a natural-language instruction to suppress the sound associated with the removed visual object from the original audio mixture. To acquire high-quality training data, we devise a pipeline to construct a million-scale dataset of single-object audio-visual aligned samples, from which we synthesize mixture-target pairs customized for model training. To effectively leverage visual context and follow instruction intent, we augment the model architecture with task tokens, generalizable instruction modeling, and modality-specific global guidance. We further adopt multi-task training to strengthen task-role comprehension, and employ a hard-mixture curriculum that leverages semantically similar acoustic mixtures during fine-tuning to enhance fine-grained source discrimination. To support evaluation, we present AV-Remove-Bench, a comprehensive audio-visual object removal benchmark, along with dedicated objective metrics and an MLLM-based evaluation protocol. Experiments demonstrate that our method achieves state-of-the-art performance on both subjective and objective metrics. Project page: this https URL.
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URL
https://arxiv.org/abs/2609.25864
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SRF-SVB: Style-Consistent Singing Voice Beautifying via Rectified Flow
2026-09-22 03:07:36Wenhui Li, Biao Dong, Liwei Hu, Jiqing Han, Yongjun HeAbstract
Singing voice beautifying (SVB) aims to correct pitch and rhythm of amateur singing while enhancing vocal quality, preserving lyrics and the singer's timbre. Existing methods, however, suffer from limited generation quality and efficiency, and tend to neglect the preservation of the singer's style. We propose SRF-SVB, a style-consistent model for SVB via rectified flow, which achieves high-fidelity and efficient beautification covering pitch and rhythm correction. Furthermore, we design a context-guided masked mel-spectrogram inpainting mechanism that effectively preserves the amateur singer's style, including unique timbre and expressive patterns. Experiments on both English and Chinese test sets show that SRF-SVB outperforms baseline models in most objective and subjective metrics.
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URL
https://arxiv.org/abs/2609.25610
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CoaG: Cylinders on a Grid: Coarse 3D Layout Control for Video Generation
2026-09-21 07:28:10Zhangsihao Yang, Mengyi ShanAbstract
We ask how little geometry a person has to draw to control both where people stand and where the camera moves in a generated video. Our answer is a ground plane and one cylinder per person. A user draws a grid on the ground, places one cylinder where each person should stand, moves the cylinders and the camera over 81 frames, and the model renders a photoreal video in which the people occupy the cylinders' positions, move as the cylinders move, and are seen from the drawn camera. Appearance comes from a text prompt and a background reference image; layout and motion come from the geometry. Because no dataset pairs such a signal with video, we build the pairs ourselves: an automatic engine writes 2000 captions from a combinatorial seed, generates a clip for each with a text-to-video model, and lifts every clip back to its geometry with person tracking, background inpainting, an agentic ground-mask loop, feed-forward multi-view reconstruction and a plane fit, with no real footage and no manual labels. A LoRA on Wan2.2-Fun-Control trained on 1935 such tuples follows drawn layouts and camera paths on hold-out clips: the generated people match the cylinders' count, order, position and height, the text changes who they are, the reference image changes where they are, and dolly-in, orbit, pan and crane paths are followed, dolly-out only weakly.
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URL
https://arxiv.org/abs/2609.24208
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Patch-to-Global: Random Patch Diffusion for Globally Consistent Megapixel Artifact Inpainting in Whole Slide Images
2026-09-21 05:12:46Hyeseong Lee, Eunsu Kim, D M Bappy, Ho Heon Kim, Youngsuk Lee, Se Young Chun, Jang-Hwan Choi, Sung Hak Lee, Sangjeong AhnAbstract
Although deep learning has advanced Whole Slide Image (WSI) Analysis, tissue artifacts like bubbles and folds often cause silent failures by concealing essential morphology. Current pathology image restoration methods are mostly restricted to small patches, struggling to maintain global structural coherence at a megapixel scale. We introduce RestorePath, a framework for globally consistent megapixel scale inpainting that reconstructs diagnostic structures in histological image to prevent incorrect high-confidence predictions and lower error rates. Our model utilizes a Latent Diffusion Model (LDM) conditioned on Pathology Foundation Model (PFM) embeddings, integrating Large Kernel Attention (LKA) to manage long-range dependencies during random patch diffusion. Enhanced by Distance-Weighted Interpolation (DWI) and an Adaptive Guidance Scale (AGS), RestorePath ensures structural consistency and fidelity by modulating information from surrounding patches. Evaluations across TCGA-BRCA, BACH, and Camelyon16 datasets for images ranging from 512 to 4608 pixels demonstrate state-of-the-art performance in maintaining histological consistency. RestorePath significantly improves downstream Computational Pathology (CP) tasks, outperforming both raw artifact images and the conventional Detect-and-Discard (D&D) approach. The code is available at this https URL
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URL
https://arxiv.org/abs/2609.24116
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AniPrO: Interpretable Anime Image Provenance Detection via Multi-Dimensional Semantic Reasoning
2026-09-20 04:15:15Yan Liu, Baoxiang Huang, Zi'an Wang, Wenbo XieAbstract
As generative AI becomes increasingly used in anime-style image creation, distinguishing human-drawn, AI-inpainted, and text-to-image images is important for copyright attribution, visual provenance, and content governance. Existing AI-generated image detectors mainly target real-world photographs and often overlook anime-specific cues such as flat coloring, exaggerated structures, and artistic line control. To address this gap, we propose AniPrO, a multi-dimensional description-enhanced framework for interpretable anime image provenance. Built upon AnimeDL-2M, AniPrO contains 15,000 balanced samples from a 35,000-image candidate pool, covering Real, Inpainting, and Text2Image categories with structured five-dimensional descriptions. We further introduce AniPrO-SFD-Bench and AniPrO-MFR-Bench to evaluate provenance detection from statistical feature discrimination and multimodal fusion reasoning perspectives. Experiments show that structured semantic guidance reveals systematic AI-generation biases, such as the gap between global visual plausibility and local detail coherence, and improves the detection of challenging inpainting samples. The dataset and code will be released at: this https URL.
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URL
https://arxiv.org/abs/2609.23345
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C$^{2}$-INR: Customized Convolutional Implicit Neural Representation
2026-09-19 06:17:17Jinglei Shi, Xinran Chang, Jiaqi Cui, Yingjie Xia, Zhaolin Xiao, Chongyi LiAbstract
Implicit Neural Representation (INR) leverages neural networks to represent discrete signals such as images as continuous ones, where the network weights serve as a compact form of the signal itself. Most existing INR methods adopt Multi-Layer Perceptrons (MLPs) as their backbone. Since these models render each pixel independently, they inherently fail to exploit the spatial correlations that exist between neighboring pixels. In contrast,convolutional INRs can process pixels in parallel while inherently accounting for inter-pixel dependencies, making them a more natural fit for representing images. Nevertheless, convolutional INRs remain relatively underexplored, and the majority of them rely on fixed architectural settings, leaving little room for image-specific adaptation. In this paper, we investigate network customization for convolutional INRs. We replace conventional filters with irregular directional kernels, whose allocation is guided by the directional energy in the image spectrum, i.e., directions exhibiting stronger energy are assigned a larger number of kernels, enabling content-tailored convolution settings. These kernels are further reformulated via an orthogonal basis to achieve a superior sparse representation. Moreover, we introduce an annealed Gumbel-Softmax-based mechanism for kernel-level activation function selection, which gives the most suitable activation function for each convolution kernel. Extensive experiments demonstrate that our method, namely C$^{2}$-INR, achieves superior performance against state-of-the-art approaches under comparable parameter budgets across a wide range of image processing tasks, including representation, inpainting, and super-resolution.
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URL
https://arxiv.org/abs/2609.22807
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Diffusion-Based Tumor Inpainting for Renal Segmentation under Clinical Data Scarcity
2026-09-18 12:34:49Ekaterina Sedykh, Salme Ussanov, Dmytro Fedorenko, Dmytro FishmanAbstract
Deep learning segmentation of renal tumors requires large annotated datasets, yet clinical deployments typically offer only a handful of tumor-positive cases from the target site. We propose a diffusion-based inpainting framework that synthesizes anatomically plausible renal tumors within healthy CT scans, requiring no additional annotation, and provide the first systematic comparison of 2D, 2.5D, and full 3D (MAISI) synthesis strategies for this task. Training the diffusion model on public data (KiTS23, KIRC) and evaluating nnU-Net segmentation on a internal cohort across three low-data regimes, we find that 2.5D and 3D augmentation substantially reduce false positives (from $\sim$18--20\% to $\sim$3--6\%) while maintaining Dice, whereas 2D provides no consistent benefit. Crucially, the proposed 2.5D method matches full 3D synthesis on every metric at substantially lower computational cost, indicating that local volumetric consistency alone is sufficient for effective augmentation in data- and resource-scarce clinical settings.
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URL
https://arxiv.org/abs/2609.21698
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