Quantitative
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EchoDiST: Self-distillation-based joint learning for diffusion-conditioned echocardiographic myocardial motion estimation
2026-10-08 07:55:08Feiyue Qi, Xingyue Wei, Jianwen LuoAbstract
Motion estimation in echocardiography is essential for quantitative assessment of cardiac function and myocardial mechanics, but remains challenging due to image artifacts, limited image information, speckle decorrelation, and the scarcity of ground-truth displacement fields. Anatomy-guided approaches can provide structural information, yet often rely on expert-labeled myocardial segmentations. We propose EchoDiST, a framework for unsupervised echocardiographic myocardial motion estimation that integrates self-distillation-based joint learning with a diffusion-conditioned motion estimation network. Here, unsupervised motion estimation refers to learning without ground-truth displacement fields. The self-distillation strategy jointly optimizes anatomical segmentation and myocardial motion estimation under limited anatomical annotations. Diffusion-based conditioning is used during training with stochastic perturbations, while inference requires only a single deterministic forward pass without iterative reverse-diffusion sampling. EchoDiST was evaluated on three echocardiographic datasets, including two external test datasets under cross-view and cross-dataset settings. Compared with seven representative learning-based methods, EchoDiST consistently improved anatomical alignment, myocardial strain assessment, and motion-derived functional and cardiac-phase assessment. These gains were statistically significant across the evaluated tasks and datasets. Overall, EchoDiST provides an effective approach for reliable myocardial motion estimation under limited anatomical supervision and supports downstream quantitative assessment of cardiac function.
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URL
https://arxiv.org/abs/2610.11431
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EvoSim: Learning to Model, Modeling to Learn
2026-10-08 06:39:07Yun-Wei Song, Jinkai Tao, Jun-Dong Zhang, Rui Zhang, Yi-Min Wu, Qiang ZhangAbstract
Physics-based models connect scientific explanation with quantitative prediction. Constructing them requires selecting physical processes, defining states and governing equations, specifying couplings, and identifying parameters from experiments. Existing AI systems remain limited in making these model structure decisions autonomously. We introduce EvoSim, a self-evolving AI scientist for physical modeling. It uses experimental discrepancies to drive mechanism and equation revisions and held-out experimental data to test physical plausibility. Exploration traces make updates to knowledge, skills, and multi-agent orchestration. This co-evolution improves physics-based models and EvoSim's ability to select mechanisms, diagnose failures, and coordinate research. We evaluate EvoSim on two industrial battery modeling tasks. It predicts lithium-metal-plating onset from 25 to 45 degrees Celsius and 2 C to 6 C with a mean absolute error of 1.79% in state of charge. Dynamic voltage prediction under vehicle driving conditions achieves a root mean square error of 7.62 mV, surpassing the reported accuracy of models developed by human experts. Self-evolution reduces model and physics errors by approximately 36% relative to baseline, demonstrating improved scientific modeling capability. EvoSim turns experimental observations into validated models and cumulative research expertise.
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https://arxiv.org/abs/2610.11344
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TRACE: A Governance Framework for Measuring Explainability Debt in Production AI Systems
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Production AI systems deployed in high-stakes domains accumulate a governance liability that existing monitoring frameworks fail to detect: the progressive inability to explain individual decisions when regulators, auditors, or affected individuals demand accountability. We introduce TRACE (Transparency, Risk, Accountability, Compliance, and Explainability), a seven-instrument governance framework for measuring, tracking, and remediating Explainability Debt in production AI systems. The foundational instrument, the Explainability Debt Score (EDS), quantifies the proportion of production decisions falling below a governance-defined explainability confidence threshold at any point in time. Complementary instruments include DART (Debt Accumulation Rate Tracker for breach forecasting), SHIV (Scenario Health and Integrity Validator for daily governance), FDE (Feature Drift Evaluator for causal attribution), HVE (Human Validation Engine), AIDE (Audit Intervention Decision Engine), and ZERO (Zero Explainability Risk Optimiser for remediation). Through a twelve-month longitudinal case study of a production fraud detection system processing 50,000 daily financial transactions, achieving 98.46% accuracy and ROC-AUC of 0.9990, we demonstrate that an EDS of 0.23 on audit day was statistically predictable six months in advance using DART trajectory analysis (beta = 0.008/week, R-squared = 0.94, 95% CI: [0.006, 0.010]), and that 78% of Explainability Debt was concentrated in the highest-regulatory-risk decision category (transactions above $10,000), a risk asymmetry completely invisible to system-level metrics. TRACE provides the first quantitative operational architecture for EU AI Act Article 13 compliance in production AI deployment, establishing a new subdiscipline of explanation governance distinct from explanation generation.
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https://arxiv.org/abs/2610.10957
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Design of a Fully Actuated 4-DOF Robotic Finger With Joint-Specific Hybrid Remote Actuation
2026-10-07 14:48:53Hyojae Kang, Hyun-mok Jung, Joonho Lee, Dongil Park, Hyunmin Do, Jongwoo Park, Jeongdo AhnAbstract
This paper presents a fully actuated 4-DOF robotic finger using a joint-specific hybrid remote-actuation architecture. The metacarpophalangeal (MCP) joint is driven by two coordinated rigid-link transmission sets, whereas the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints are independently actuated by closed-loop wire transmissions incorporating circular rolling-contact joints (RCJs). A larger transmission radius is used at the PIP joint than at the DIP joint. The RCJ wire geometry maintains the total wire-loop length during joint rotation, and the DIP wire routing is designed so that PIP motion does not affect its differential actuation for a fixed MCP configuration. The distal wire transmission, MCP linkage, and fingertip kinematics are analytically modeled. In experiments, the transmission behavior was quantitatively evaluated from the ball-screw displacements measured using ArUco-marker tracking. MCP actuation produced measurable displacements of the PIP and DIP transmission units, whereas isolated PIP and DIP actuation with the MCP fixed supported the intended mechanical decoupling between the distal transmissions. The mean peak fingertip forces under isolated MCP, PIP, and DIP actuation were 21.28 N, 9.22 N, and 5.75 N, respectively. The resulting finger postures were also examined using objects of different geometries and sizes.
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URL
https://arxiv.org/abs/2610.10180
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CIRSeg: Coarse-to-Fine Intensity-Robust Liver Segmentation with Source-Free Continual Test-Time Adaptation
2026-10-07 10:02:27Ruoshi Xu, Mingqi Gao, Shengda Luo, Jingkun ChenAbstract
Reliable liver segmentation in contrast-enhanced MRI is essential for quantitative hepatic assessment, treatment planning, and longitudinal disease monitoring. However, limited annotated data and scanner- or vendor-dependent intensity variations can cause overfitting and poor generalization to unseen acquisition domains. Moreover, simultaneously achieving robust global localization and precise boundary delineation remains challenging, while predictions may contain isolated false-positive regions outside the main liver component. To address these challenges, we propose CIRSeg, a coarse-to-fine, intensity-robust liver segmentation framework based on nnU-Netv2. CIRSeg combines 3D CutMix with stochastic intensity transfer using either Nyul augmentation or histogram matching to improve robustness to heterogeneous MRI intensities. Its cascaded architecture decouples low-resolution anatomical localization from full-resolution boundary refinement. At inference, source-free test-time adaptation based on confidence-filtered predictions and probability-prior regularization further improves robustness to out-of-distribution inputs. As a final deterministic post-processing step, largest connected component filtering removes isolated false-positive regions. On the CARE 2026 test set, CIRSeg achieves Dice scores of 97.13\% and 97.93\% on the in-domain and unseen-domain subsets, with corresponding HD95 values of 20.18 mm and 11.30 mm, respectively. These results demonstrate consistently accurate segmentation across both in-domain and unseen acquisition settings. The code is available at this https URL
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URL
https://arxiv.org/abs/2610.09784
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Enhancing Multi-Region Stylization with Interior-Guided Boundary Repair
2026-10-07 09:03:24Hong-Son Nguyen, Thi-Ngoc-Hanh LeAbstract
Region-based neural style transfer enables fine-grained artistic control by allowing independent stylization of semantic image regions. However, compositing these regions often leads to boundary artifacts, degrading visual quality. We propose Interior-Guided Boundary Repair (IGBR), a lightweight and model-agnostic method that improves boundary handling in multi-region stylization. IGBR repairs boundary pixels using interior-guided propagation and applies inward, distance-based blending restricted to object-background boundaries, preventing inter-object style leakage. The method is derived from a region-wise constrained formulation with a closed-form solution and can be seamlessly integrated into existing stylization pipelines without retraining. To evaluate efficiency of our IGBR, we introduce quantitative metrics that measure boundary consistency, gradient artifacts, inter-object leakage, and interior preservation without requiring annotated stylized images. Our experiments and evaluations demonstrate that the proposed IGBR consistently produces plausible boundaries, outperforming prior blending techniques in boundary consistency, gradient stability, and interior preservation. The code is available at this https URL.
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URL
https://arxiv.org/abs/2610.09706
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PPCAR-Net: Projection-Refined Parametric 3D Coronary Artery Reconstruction from Sparse X-ray Angiographic Views
2026-10-07 03:40:36Yu Ren, Hwee Kuan Lee, Tat-Jen Cham, Jonathan Yap, Khung Keong YeoAbstract
Sparse-view 3D coronary reconstruction commonly relies on cross-view correspondence and triangulation, which are vulnerable to vessel overlap and foreshortening, or on volumetric prediction followed by vascular-graph extraction, which does not directly provide centrelines and radii. We introduce PPCAR-Net, a projection-refined parametric coronary artery reconstruction network that directly predicts a branch-structured centreline-and-radius representation without explicit point matching, triangulation, or an intermediate volume. Given a variable number of segmented views, a coarse predictor combines frozen VGGT features with learned branch queries to estimate branch presence, B-spline centreline trajectories, and dense radius profiles. Projection-guided geometry and radius refiners then sample local evidence from the input views and apply residual corrections learned with 3D supervision. We evaluate representation fidelity and sparse-view reconstruction quantitatively and qualitatively. On simulated angiographic masks generated from CT-derived coronary anatomy, PPCAR-Net produces better connected artery reconstructions and achieves strong centreline accuracy, particularly for RCA, while maintaining competitive volumetric overlap. Coarse-to-fine inference takes 121 ms, enabling real-time reconstruction.
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URL
https://arxiv.org/abs/2610.09383
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FaceKit: a Toolkit for Interpretable Facial Phenotyping, Synthetic Image Generation and Privacy Analysis in Rare Diseases
2026-10-07 01:43:49Hongzhuo Chen, Zhanliang Wang, Florent Pollet, Mian Umair Ahsan, Joshua Bie, Tzung-Chien Hsieh, Peter Krawitz, Cong Liu, Wendy K Chung, Chunhua Weng, Gamze G\"ursoy, Kai WangAbstract
Many rare genetic diseases are associated with recognizable craniofacial features. However, traditional approaches for describing facial morphology rely largely on qualitative clinical observation and free-text descriptions, which are often subjective, non-standardized, and difficult to reproduce across observers and institutions. Although the Human Phenotype Ontology (HPO) provides controlled terms for describing facial features, these terms are typically categorical rather than quantitative and may vary depending on examiner experience and interpretation. Here, we present FaceKit, a computational framework for quantitative facial phenotyping from frontal facial photographs. FaceKit extracts standardized measurements of facial landmarks and derived 120 morphological features, then reports feature-level z-scores representing deviation from population reference distributions. The reference distributions are built from the FairFace dataset spanning diverse ancestral groups. We evaluated FaceKit on a curated subset of the GestaltMatcher Database covering 50 rare-disease cohorts. In addition to quantitative facial analysis, FaceKit includes synthetic facial image generation to support rare disease model development and data augmentation. We also performed privacy evaluation to assess whether synthetic images reveal identifiable information from real patient photographs and could compromise patient privacy. Across disease case studies, FaceKit-derived quantitative measurements captured known facial features associated with rare genetic disorders and provided objective support for clinical phenotyping. Together, these results establish FaceKit as a useful tool for quantitative phenotyping, and has the potential to improve rare disease diagnosis, support genotype-phenotype studies, and enable more reproducible clinical characterization across diverse patient populations.
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URL
https://arxiv.org/abs/2610.09288
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LeCuration: A Tiny World Model as a Data Curation Multi-Tool
2026-10-07 01:41:23Mayank Sengupta, Nirmit Desai, Eric Song, Kunal SawarkarAbstract
Many applications of physical AI run within finite or closed physical worlds with a limited set of physical laws governing object behavior. Examples include robots working in a warehouse and agents moving around in a video game. In order to better organize, filter, and curate data for physical AI applications, we propose a new approach centered on the unique settings and physical laws of individual datasets. We train LeCuration, a small world model intended to serve as a data curation tool for a separate, larger downstream model. To build this model, we choose LeWorldModel (LeWM)as our latent encoder and predictor, adding a diffusion transformer (DiT) decoder to add visuals to autoregressive gameplay rollout. We find that the embeddings of this model can be used as an anomaly detection signal and as a content-based clustering heuristic, and that auto-regressively predicting the game state with this model allows us to qualitatively check for action-state consistency. This paper presents a qualitative, proof-of-concept case study on CS:GO gameplay data; we do not yet report quantitative curation metrics or downstream training results, which we identify as the key next step.
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URL
https://arxiv.org/abs/2610.09285
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Zero-Shot Brain MRI Inpainting with 2.5D Unconditional Flow Priors
2026-10-06 18:44:24Arnela Hadzic, Franz Thaler, Simon Johannes Joham, Martin UrschlerAbstract
Generative inpainting of brain MRI volumes is essential for synthesizing healthy tissue in pathological regions, improving the accuracy and reliability of automated downstream brain analysis applications such as image registration, brain extraction, and segmentation. However, standard 3D approaches are computationally prohibitive, while efficient 2D slice-wise methods suffer from severe inter-slice discontinuities. Furthermore, traditional models rely on conditional training, requiring task-specific learning of masked inputs. We propose a zero-shot brain MRI inpainting framework utilizing 2.5D unconditional flow priors to capture spatial context along the superior-inferior axis without the overhead of full 3D convolutions. During training, our flow matching model learns the joint distribution of adjacent axial slice triplets, modeling the manifold of healthy brain anatomy while explicitly excluding pathological regions from the loss function. At inference, the model processes the input triplets autoregressively along the depth axis. We employ the Restora-Flow solver to constrain the unconditional prior using the input mask, achieving accurate zero-shot inpainting. Evaluations show our 2.5D strategy resolves the structural discontinuities of 2D baselines, synthesizing plausible healthy tissue while maintaining volumetric consistency across the axial, sagittal, and coronal planes. As a final step, we generate and average an ensemble of multiple stochastic reconstructions to form the final prediction. Quantitative results benchmarked on the official BraTS 2026 Inpainting Challenge validation set demonstrate the effectiveness of our proposed approach, yielding an SSIM of 0.816 $\pm$ 0.112, MSE of 0.007 $\pm$ 0.005, and PSNR of 22.923 $\pm$ 4.343. Code is available at this https URL.
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URL
https://arxiv.org/abs/2610.08983
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World Models' Last Exam in Physics
2026-10-06 17:59:56Mingju Gao, Qingle Liu, Yuzhao Peng, Xinjie Lin, Ziming Qin, Zheng Jiang, Wenyi Li, Calvin Xiao, Youjie Zheng, Kaisen Yang, Qinhuai NaAbstract
Video world models can produce visually convincing yet physically inconsistent sequences, raising concerns about their reliability for prediction and planning in embodied AI systems. Existing evaluations often rely on model-based judgments or reference videos, while direct physical tests largely focus on mechanics. We introduce World Models' Last Exam in Physics, a measurement-based benchmark for evaluating physical consistency in video world models. The benchmark comprises 40 controlled tasks spanning mechanics, optics, fluids, thermal and phase-change phenomena, electromagnetism, and surface tension. Each task pairs an initial image and a generation prompt with predefined physical criteria, enabling interpretable tests of observable physical relationships without requiring reference videos. Its evaluator combines task-observability screening with task-specific quantitative physical measurements. Experiments on eight video generation models across 1,280 videos reveal persistent physical inconsistencies and substantial variation across tasks, with the best model achieving an overall score of 57.76 out of 100. Evaluation on synthetic videos with known physical relationships provides evidence for the validity of the measurement module under controlled conditions. The evaluator also achieves higher agreement with human judgments than a direct vision-language model baseline in both within-task rankings and pairwise comparisons. By combining coverage across physical domains with scores grounded in measurable evidence and explicit measurement limitations, the benchmark provides an interpretable basis for diagnosing physical inconsistencies and tracking progress toward physically consistent video world models.
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https://arxiv.org/abs/2610.08791
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Feature Information Dynamics in Diffusion
2026-10-06 16:24:07Jia-Shu Pan, Tao Zhang, Yufei Huang, Yanjun Sheng, Tailin WuAbstract
Diffusion models generate data through a continuum of denoising problems, and are widely observed to reveal coarse structure before fine detail. Yet, this intuition is mostly empirical and qualitative. We introduce feature information dynamics, an information-theoretic framework for localizing when a feature is generated during diffusion. Using the I-MMSE identity, we connect the rate of feature mutual information change to a gap between optimal unconditional and feature-conditional denoising losses, yielding practical estimators for feature information density. We further develop a chained decomposition that separates shared from incremental information in a feature hierarchy. We use this framework first to quantitatively confirm spectral autoregression in pixel diffusion, and then to extend the analysis beyond frequency: under a class $\to$ mask $\to$ Canny conditioning chain, the per-feature information densities differ across pixel, SDVAE, VAVAE, and RAE, exposing fundamental differences between these representations and suggesting that ordered generation could be beneficial for training diffusion models. Our code is available at this https URL.
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https://arxiv.org/abs/2610.08626
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MedCORE: Criteria-Grounded Clinical Reasoning for Interpretable Medical Image Diagnosis
2026-10-06 15:23:01Asim Khan, Samee Ullah Khan, Dwarikanath MahapatraAbstract
Clinical diagnosis is inherently a structured reasoning process, yet existing deep learning models often bypass this structure by mapping image features directly to disease labels without explicitly interrogating the morphological and textural criteria that clinicians systematically evaluate. This limits diagnostic transparency and may compromise safe clinical deployment. We present MedCORE (Medical Criteria-Oriented Reasoning and Evidence), a structured diagnostic framework that operationalizes clinical reasoning within a vision-language architecture. For each input image, MedCORE decomposes the diagnostic process into clinically defined criteria, spatially localizes each criterion to diagnostically relevant image regions, encodes evidence through multi-scale representations that capture macro-structural and micro-textural pathological characteristics, and refines criterion representations using a Graph Attention Network that explicitly models inter-criteria dependencies. Criterion representations are further aligned with clinical text descriptors, reinforced through class-wise visual prototypes, and aggregated using uncertainty-calibrated weighting that proportionally discounts low-confidence diagnostic evidence. MedCORE is validated across three clinically heterogeneous imaging modalities, including dermoscopic lesion classification on ISIC 2018, breast ultrasound lesion characterization on BUSI, and diabetic retinopathy grading on IDRiD. Quantitatively, MedCORE achieves 89.2% accuracy, 85.7% macro-F1, and 96.4% AUC on ISIC 2018; 96.1% accuracy, 95.2% macro-F1, and 98.4% AUC on BUSI; and 84.3% accuracy, 80.2% macro-F1, and 92.8% AUC on IDRiD. These results demonstrate consistent improvements over strong CNN, transformer, biomedical vision-language, concept-based, and prototype-based baselines.
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https://arxiv.org/abs/2610.08528
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Multitask Conditional Generative Adversarial Network Enables Automatic Whole Knee Cartilage and Menisci Segmentation and Reliable $T_{1rho}$ and $T_2$ Quantification Without High-Resolution Morphological Images
2026-10-06 11:58:45Ahmed Tahseen Minhaz, Richard Lartey, Zhiyuan Zhang, Jeehun Kim, Kunio Nakamura, Mingrui Yang, Jiasen Zhang, Weihong Guo, Naveen Subhas, Carl S. Winalski, Xiaojuan LiAbstract
Early osteoarthritis detection through quantitative MRI (qMRI) requires accurate cartilage and meniscus segmentation, traditionally necessitating time-consuming, costly 3D high-resolution Double Echo Steady-State (DESS) MRI scans. This study developed a multi-task conditional generative adversarial network (MT-cGAN) to simultaneously synthesize DESS-like images and segment tissues directly from qMRI echo images. This retrospective study evaluated 508 knee MRI volumes from 361 subjects (mean age: $40.4 \pm 12.2$ years; 179 female) across three cohorts. Ground truth segmentation masks were generated from DESS images using a pretrained model with manual correction, and $T_{1\rho}$ and $T_2$ maps were computed from magnetization-prepared angle-modulated partitioned $k$-space spoiled gradient echo snapshots (MAPSS) echo images. MT-cGAN was trained to jointly synthesize DESS-like images and segment cartilage and meniscus directly from echo images. Model performance was evaluated using Dice score for segmentation accuracy and coefficient of variation (CV) for $T_{1\rho}$ and $T_2$ quantification. MT-cGAN achieved the highest segmentation performance, mean Dice score 0.84 (range: 0.80--0.86) across all cartilage and meniscus compartments and significantly outperformed the state-of-the-art conditional GAN model with transfer learning (mean Dice, 0.82; $p < 0.001$, Wilcoxon signed-rank test). For relaxometry quantification, MT-cGAN demonstrated the highest consistency with the reference DESS protocol, yielding the lowest CV ($T_{1\rho}$: 1.84%, $T_2$: 1.81%). The proposed MT-cGAN accurately segmented cartilage and menisci while providing reliable $T_{1\rho}$ and $T_2$ quantification directly from echo images. By eliminating the need for separate morphological DESS scans, this workflow reduces required scan times to facilitate the clinical translation of qMRI.
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URL
https://arxiv.org/abs/2610.06602
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Comprehensive Evaluation and Fine-Tuning of Foundational Cell Nuclei Segmentation Models in Renal Pathology
2026-10-06 04:05:49Ruijie Wu, Junlin Guo, Ruining Deng, Yu Wang, Shilin Zhao, Haichun Yang, Yuankai HuoAbstract
Accurate nuclei instance segmentation is essential for quantitative renal pathology, yet general-purpose models often struggle with low contrast, dense nuclei, complex morphology, and strong background staining. In this work, we extended a human-in-the-loop framework by combining 5,901 foundation-model-generated pseudo-labels from well-segmented cases (Easy), 860 newly expert-annotated unresolved challenging cases (Medium), and 198 expert-annotated consensus failure cases (Hard). These annotations, spanning different levels of segmentation difficulty, enabled the systematic evaluation of seven single-source and mixed-source fine-tuning strategies across nine cell segmentation model configurations. Fine-tuning improved all models, with Medium data included in seven of the nine best-performing strategies. LSP-DETR achieved the highest F1 score of 0.8725 with Hard-only fine-tuning, while StarDist showed the largest improvement, increasing from 0.7380 to 0.8332 with Medium-only fine-tuning. These findings show that annotations spanning multiple difficulty levels support effective model adaptation, although the optimal annotation composition remains model dependent.
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https://arxiv.org/abs/2610.07711
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On the Boundary of Admission Gates: An Injected-Truth Study of Falsification-First Selection in Quantitative Strategy Research
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Strategy research conflates two problems: finding a profitable rule, and establishing that the finding is not search luck. The latter calls for admission gates -- statistical criteria that must be satisfied before a conclusion is adopted -- yet whether gates work, and at what cost, remains untested. We introduce an injected-truth protocol with a random-admission control that adopts at the same rate as the gate; only if the gate beats this control does it carry information rather than merely raise a threshold. Across synthetic and real-calibrated panels, gates eliminate false discoveries in the weak-signal regime but cut adoption to 1--7%, and add nothing when signals are strong. Most importantly, criteria computed on absolute rather than excess returns silently reject every candidate, including true signals. Keywords: multiple testing, backtest overfitting, strategy admission, injected-truth validation, excess returns, false discovery rate
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https://arxiv.org/abs/2610.07701
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RPA: Residual Patch-Token Adapter for Image Retrieval from EEG and MEG
2026-10-06 01:25:45Yuhui Jin, Yonghao Song, Bingchuan LiuAbstract
Most existing MEG and EEG (M/EEG) visual decoding methods align brain signals with a single global embedding extracted from a pretrained visual encoder, leaving open whether intermediate patch representations, which preserve richer and more granular rich visual information, can improve representation learning. To address this question, we introduce the Residual Patch Adapter (RPA), a lightweight, modular adapter that leverages all patch tokens from an intermediate layer of a ViT visual encoder for alignment. Through extensive ablation analyses, we first show that pooling or masking patch tokens degrades the learned representation, demonstrating that retaining the full set of patch tokens is important for EEG alignment, while the CLS token provides little unique information. We then use a series of six quantitative feature analyses to show that both higher-level semantics and lower-level visual features, including color and texture, are essential for this EEG-to-image alignment. Under current protocols, our system achieves Top-1 accuracies of 95.4\% within-subject and 35.5\% cross-subject on THINGS-EEG2, and 65.2\% and 6.7\%, respectively, on THINGS-MEG, achieving state-of-the-art (SOTA) performance across both datasets. Evaluations with alternative brain encoders, including pretrained EEG foundation models, demonstrate that the approach extends beyond the projection-based EEG encoder. Furthermore, we provide a plug-and-play interface that allows RPA to be replaced by convolution, attention, or ConvNeXt alternatives. Together, these findings provide significant insight into M/EEG-to-image representation learning by establishing design principles for leveraging the latent space of visual encoders, and open new directions for brain--image alignment and non-invasive brain--computer interface (BCI).
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URL
https://arxiv.org/abs/2609.31698
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Representation Bias, Correction Transfer, and Resolution Sensitivity in Three-Dimensional Mitochondrial Morphometry
2026-10-06 01:18:00Farouk Ganiyu Adewumi, Timothy OladunniAbstract
Quantitative imaging pipelines can produce precise but systematically different measurements of the same object. We present an empirical reliability assessment of three-dimensional mitochondrial morphometry that connects representation bias, a controlled processing intervention, correction transfer, and resolution sensitivity. Using 2,720 development objects from the 3D Mitochondria Shape Library for Optical Microscopy, we find that occupancy-derived volumes exceed reference mesh volumes by 3.665% on average despite an intraclass correlation coefficient of 0.994. Boundary analysis identifies an outward label displacement of 0.00304 normalized units. In a controlled label-pipeline reimplementation, removing the depth offset reduces volume error in all 55 analyzed objects by a mean of 1.57 percentage points, approximately 45% of mean reproduced inflation; the source of the remainder is not isolated. A frozen regression using occupancy-derived features reduces median absolute percentage error from 3.481% to 0.664% in 2,728 previously unused objects from the same resource. However, its calibrated error bound covers only 92.1% overall and 49.2% in a low-occupancy subgroup, demonstrating that accuracy and uncertainty transfer must be evaluated separately. In 550 rat-cortex objects from the MitoEM resource, coarsening in-plane spacing from 8 to 24 nanometers changes median surface area by minus 10.60% and sphericity by plus 11.76%, despite a rank correlation of 0.994. These results provide quantitative checks for distinguishing processing-induced descriptor changes from candidate biological differences, without establishing biological invariance or cross-source correction transfer.
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https://arxiv.org/abs/2610.07582
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Complementary Feature Domains: Information Preservation Does Not Imply Predictive-Contribution Preservation
2026-10-06 00:53:05Timothy Oladunni, Farouk Ganiyu-AdewumiAbstract
Complementary Feature Domains (CFD) theory characterizes predictive value as a context-indexed contribution system induced jointly by representations and their realization family. We show that Shannon-information preservation does not imply preservation of this contribution system: an invertible representation transformation can leave target information unchanged while altering predictive contribution under a restricted decision family. We formalize the resulting transition through a CFD contribution defect that measures how contextual contributions change under controlled recoding. For bounded Lipschitz utility, we show that each coalition utility shift is bounded by the behavioral distance between the attainable action sets before and after recoding; consequently, every contextual contribution defect is bounded by the sum of the corresponding coalition incompatibilities. Exact behavioral closure yields invariance, while increasingly accurate compensation yields restoration. A controlled ECG experiment illustrates the mechanism: a nonlinear bijective recoding preserves the information in a frozen time-frequency representation but changes accuracy under a fixed affine learner; applying the exact inverse restores all tested coalition accuracies. The result separates information preservation from realization-dependent contribution and provides a quantitative transition law for multi-representation prediction.
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https://arxiv.org/abs/2610.07565
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HouseholdBench: Evaluating Large Language Models as Predictors of Household Economic Behavior
2026-10-06 00:50:28Jin Huang, Diego Ferreras Garrucho, Yutong Xie, Walter M. Yuan, Qiaozhu Mei, Chen Lian, Jonathon HazellAbstract
Large language models (LLMs) have the potential to meet a key goal in economics: a quantitative model of household decision making, across a variety of settings. Yet existing evaluations cover few surveys and outcomes, and do not study how households adjust to changing economic conditions. We introduce a new evaluation, HouseholdBench, which unites 6 U.S. household surveys and 32 prediction tasks spanning numeric, categorical and probabilistic outcomes, related to consumption, income, labor, expectations, and housing. Using past behavior, demographics and macroeconomic conditions, the tasks test whether LLMs predict behavior, including how households adjust to changes in various policies. We evaluate 13 proprietary and open-weight LLMs against a no-change baseline and a gradient-boosted tree model. Most LLMs outperform the no-change baseline, including for policy response tasks -- with the best model lowering error for numeric outcomes by 12.2%. Across most tasks, gradient-boosted trees rank first; leading proprietary LLMs approach their performance, but open-weight models lag. LLMs exhibit systematic over- and underprediction across different tasks. We identify methods that enable a 4 billion parameter open-weight model to match proprietary models' performance: fine-tuning and aggregating 16 predictions per observation. Improvements generalize to policy-response tasks, which are excluded from fine-tuning. We release our datasets, code, and leaderboard on our website: this https URL
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https://arxiv.org/abs/2610.07563
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