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Self-Supervised Learning of Echocardiogram Videos Enables Data-Efficient Clinical Diagnosis

2022-07-23 19:17:26
Gregory Holste, Evangelos K. Oikonomou, Bobak Mortazavi, Zhangyang Wang, Rohan Khera

Abstract

Given the difficulty of obtaining high-quality labels for medical image recognition tasks, there is a need for deep learning techniques that can be adequately fine-tuned on small labeled data sets. Recent advances in self-supervised learning techniques have shown that such an in-domain representation learning approach can provide a strong initialization for supervised fine-tuning, proving much more data-efficient than standard transfer learning from a supervised pretraining task. However, these applications are not adapted to applications to medical diagnostics captured in a video format. With this progress in mind, we developed a self-supervised learning approach catered to echocardiogram videos with the goal of learning strong representations for downstream fine-tuning on the task of diagnosing aortic stenosis (AS), a common and dangerous disease of the aortic valve. When fine-tuned on 1% of the training data, our best self-supervised learning model achieves 0.818 AUC (95% CI: 0.794, 0.840), while the standard transfer learning approach reaches 0.644 AUC (95% CI: 0.610, 0.677). We also find that our self-supervised model attends more closely to the aortic valve when predicting severe AS as demonstrated by saliency map visualizations.

Abstract (translated)

URL

https://arxiv.org/abs/2207.11581

PDF

https://arxiv.org/pdf/2207.11581.pdf


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