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Data-driven techniques for translational neuroscience and personalized neuro-health

2026-08-13 20:11:09
Vishal Subedi, Shashipraba N. K. Rajakaruna, Pratyusha Sarkar, Subhankar Chattoraj, Anjali Khasa, Siddhartha Nandy, Hamza Farooq, Animikh Biswas, Sanjay Chaudhuri, Asim K. Dey, Karuna Joshi, Christophe Lenglet, Ansu Chatterjee
arXiv_AI
           
Abstract

Neurodegenexrative diseases such as Alzheimer's disease and Parkinson's disease are diagnosed most reliably only after substantial, often irreversible, neuronal loss has already occurred, creating an urgent need for quantitative tools that can detect subtle, early, and individual-specific brain changes from neuroimaging data. This review surveys a broad and rapidly evolving toolkit of data-driven techniques for translational neuroscience and personalized neuro-health, organized around four complementary methodological pillars. Throughout, we emphasize how these methodologically diverse approaches converge on a common translational goal: personalized, mechanistically grounded, and clinically actionable models of individual brain health, and we close by discussing the principal open statistical, computational, and clinical challenges that remain.

Abstract (translated)

URL

https://arxiv.org/abs/2608.13749

PDF

https://arxiv.org/pdf/2608.13749.pdf

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