Abstract
Pretrained representations are increasingly used to share and reuse information from medical images without exposing the original scans, but it is unclear how much patient-specific information these representations retain. We investigate this question for brain magnetic resonance imaging (MRI) by evaluating five frozen pretrained encoders spanning different architectures, pretraining objectives, and training domains on two longitudinal T1-weighted datasets, OASIS-2 and MIRIAD. Under an attacker model with access to released embeddings, the corresponding public encoder, and auxiliary MRI scans, we evaluate patient linkage and sensitive-attribute inference. Across the evaluated representations, we observe substantial subject-specific information: rank-1 patient linkage reaches up to 99\% on MIRIAD and exceeds 90\% on OASIS-2 for the highest-risk representation, despite the absence of an identification objective during encoder training. We further show that the released embeddings retain information about a demographic attribute, with recorded-sex prediction reaching balanced accuracy of 90.9\% on OASIS-2 and 95.5\% on MIRIAD. Overall, our results demonstrate that replacing raw brain MRI with learned embeddings does not, by itself, eliminate patient-linkage or attribute-inference risk, and is therefore insufficient on its own to establish anonymity.
Abstract (translated)
URL
https://arxiv.org/abs/2610.20494
